Southampton have reached an agreement with manager Ivan Juric to leave following relegation from the Premier League on Sunday.
Juric was appointed as Russell Martin’s successor on an 18-month deal in December but has won just two of his 16 matches.
Sunday’s 3-1 defeat at Tottenham consigned the rock-bottom Saints to the earliest relegation in Premier League history with eight games still to play.
The loss against Spurs was Southampton’s 25th of the season in the league.
“Ivan came to Southampton at a tough time and was tasked with trying to improve a squad in a difficult situation,” Southampton said.
“Unfortunately, we haven’t seen performances progress the way we had hoped, but we would like to thank Ivan and his staff for their honesty and hard work as they fought against the odds to try and keep us up.
“With relegation to the Championship now confirmed, we believe it is important to give fans, players and staff some clarity on the future as we head into a very important summer.”
Simon Rusk is expected to step in as interim manager with Adam Lallana acting as his assistant.
Juric lasted just 107 days at St Mary’s and oversaw only one victory in the Premier League – a 2-1 triumph at Ipswich.
His spell in charge is the ninth-shortest reign as a manager in Premier League history.
Rooted to the bottom of the standings on 10 points, Southampton require two further points to avoid beating Derby County’s record-low tally of 11, achieved in 2007-08.
Juric arrived at Southampton having been sacked by Roma in November after only 12 games in charge of the Serie A club.
The 49-year-old has previously held roles in Italy with Torino, Hellas Verona, Genoa, Crotone and Mantova.
